According to WHO, infection prevention and control (IPC) is a scientific approach and practical solution designed to prevent harm caused by infection to patients and health workers. It is grounded in infectious diseases, epidemiology, social science and health system strengthening. IPC occupies a unique position in the field of patient safety and quality universal health coverage since it is relevant to health workers and patients at every single health-care encounter. Other Guidance notes explain how UNICEF WASH programmes can contribute to IPC in Health care facilities and schools, as well as improving COVID-19 preventative hygiene behaviours in all settings.