This paper provides guidance to encourage policy-makers (particularly those within ministries of health) and health professionals in national and international organisations to consider the impact of disasters on children’s health, and calls on them to integrate DRR into all health policies and programmes. The paper applies the Hyogo Framework for Action (see page 5) to guide the priority interventions. It also provides practical examples of activities that can help build the resilience of health systems at national, local and community levels, allowing us to safeguard children’s lives before disaster strikes.