In countries across Asia-Pacific, the response to COVID-19 is escalating with serious implications for peace and security, and the rights of women and girls. The enactment of national emergency powers, introduction of military checkpoints and lockdowns, closed borders, and restrictions on citizens’ movement and speech, all mirror a governance context similar to that of a conflict setting. This brief introduces the issue, presents considerations of the implications of COVID-19 in the women, peace and security agenda and offers some recommendations on the way forward.